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In CME_a, the glutamate portion of the CME forms stable chelation with the double copper binding site, and CME forms hydrogen bonds with H84, H262, and N259 in the pocket, which greatly contributes to the overall stability

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In line with this observation, 2-hydroxybutyrate is increasingly recognized as a biomarker of metabolic disturbances, particularly in insulin resistance and glucose intolerance 27

Digestive recovery of polyphenols, antioxidant activity, and anti-inflammatory activity of selected edible flowers from the family Fabaceae

[4] As a result, GLP-1 agonists are contraindicated in individuals with a personal or family history of medullary thyroid carcinoma or those with multiple endocrine neoplasia syndrome type 2 (MEN 2), a genetic disorder that increases the risk of certain types of tumors